zinc – 47 important reasons to take zinc tablets : Zinc pills have many health benefits, including maintaining a balanced immune system, reducing inflammation and acting as an antioxidant. As the second most abundant mineral in the body after iron, zinc plays a vital role in biological processes.
Catalysis in the synthesis and metabolism of carbohydrates, fats, proteins, nucleic acids, and other nutrients requires more than 300 enzymes. Furthermore, they are crucial for maintaining cellular and organ structures, immune function, and wound healing. It is necessary for cell division, growth, blood clotting, thyroid function, vision, taste, and smell, and it is not stored in the body and must be obtained through diet.
Suitable food sources for zinc include:
Red meat, seafood, dairy products, nuts, legumes, and whole grains absorb more zinc than animal products. Because they contain phytate, a compound found in plants that inhibits zinc absorption, vegetables are not a good source. Since this substance plays a crucial role in the immune system, its deficiency leads to a number of diseases, and its lack is therefore one of the most critical public health issues. People with digestive disorders, vegetarians, pregnant and lactating women, alcoholics, and those with sickle cell disease are at risk for zinc deficiency.
Benefits of Zinc Pills, Oral Supplements, and Natural Resources:
Boost the immune system and reduce the risk of infection
Many immune cells rely on zinc for growth and function. Even mild deficiencies can impair immune function and increase the risk of bacterial, viral, and parasitic infections due to its vital role in the immune system. Mineral pills can increase the activity of natural killer cells, the production of lymphocytes, and resistance in diseases associated with a weakened immune system (e.g., sickle cell disease, HIV infection, Down syndrome, and the elderly).
Supplements are associated with reducing infections and a reduced risk of immunodeficiency in people with HIV who have low zinc levels in their blood.
Supplements should be taken with caution, as too much zinc may worsen symptoms. People with enteropathic acrodermatitis (a genetic disorder that affects absorption) tend to get infected more often. Zinc tablets at total therapeutic doses cause complete recovery.
A number of studies have shown that zinc consumption in infants and children in developing countries reduces the duration, severity, and prevalence of acute and chronic diarrhea, acute respiratory infections, and malaria.
Other infectious diseases in humans have been reported to have similar effects, including shigellosis, leprosy, tuberculosis, leishmaniasis, hepatitis C, and colds (increased Th1 cytokines).
However, excessive amounts of this mineral may suppress the immune system. The study found that high doses of zinc reduced several immune functions in healthy men, including activation of lymphocytes, phagocytosis, and neutrophils.
It has an antioxidant role.
Zinc tablets could decrease blood lipids in the elderly, and another study found that zinc could reduce DNA damage in women. Fractures in DNA are commonly used as parametric markers to assess damage caused by oxidative stress.
In addition, zinc tablets restore superoxide radical scavengers to normal levels in the sperm of men with asthenospermia (poor sperm motility) and protect mice from oxidative stress caused by radiation.
The mineral pill has also been proven to treat Wilson’s disease, a condition in which zinc accumulates in body tissues and prevents skin cells from dying from oxidative stress and bacterial toxins.
Help reduce and control inflammation.
Zinc inhibits several inflammatory cytokines. Studies in the elderly (often deficient in zinc) have shown that zinc reduces inflammation by reducing cytokines and other inflammatory markers, as well as treating irritable bowel syndrome, acne, and various inflammatory disorders.
In older mice, tablets have lower levels of age-related inflammatory markers.
To fight asthma and allergies.
Grass pollen, an allergen that causes allergic rhinitis in many parts of the world, increases regulatory lymphocytes and reduces peripheral blood mononuclear cells (PBMCs).
A low level of zinc in the blood is associated with severe asthma symptoms in children. Zinc pills were found to improve asthma symptoms (such as coughing, wheezing, and shortness of breath) in children.
In mice with allergic inflammation and asthma, it can reduce inflammation and overreaction of the airways. Zinc-sensitive allergens can prevent death of respiratory epithelial cells (by inhibiting caspase-3).
Preventing transplant rejection
Zinc can inhibit the unwanted immune response by stimulating regulatory lymphocytes. In a study of healthy men, this mineral was shown to prevent rejection by preventing infections caused by immunosuppressive disorders.
A laboratory study found that zinc reduced inflammation, suppressed T lymphocyte proliferation, and increased regulatory lymphocytes in mice with multiple sclerosis (MS) and osteoarthritis. Mixed cultures of lymphocytes stimulate T lymphocytes in the regulator and decrease bonding by reducing inflammatory cytokines and T lymphocytes.
In a rat model of heart transplant rejection, this mineral reduced rejection by preventing transplant tissue death (by inhibiting caspase-3). After a change in the positive changes in joint swelling, stiffness in the morning and after walking was observed in patients with rheumatoid arthritis.
Enhance cognitive function and protect nerve cells
When people with zinc deficiency experience an ischemic stroke, zinc tablets can improve cognitive function. Compared to controls, a double-blind trial in children showed that the pill helped improve nerve function, especially attention and logic.
Zinc tablets in infants and toddlers increased their activity, mental development, and motor skill quality, according to a randomized trial. Zinc consumption in Alzheimer’s patients reduces blood copper levels, which can be toxic to the brain.
In animal studies, zinc at moderate concentrations has been shown to protect nerves and maintain learning and memory.
The pill reduces pathological factors associated with the progression of Alzheimer’s disease (such as amyloid-beta and tau protein). In the hippocampus, it increases mitochondrial function and brain-derived neurogenic factor (BDNF). Another study showed that zinc pills increased spatial memory and memory in mice.
Accelerate wound healing
It has been shown to heal wounds, and its deficiency results in delayed wound healing. Studies have shown that zinc can accelerate the healing of burns and other wounds after surgery.
When applied topically, zinc oxide improves the healing process of shear wounds in rats.
It can also be used to treat mental disorders.
Adding zinc to fluoxetine treatment reduced symptoms in OCD patients, according to a study. Since zinc prevents the release and transmission of glutamate, it can also improve OCD symptoms.
In one study, zinc tablets combined with methylphenidate (a CNS stimulant) reduced hyperactivity and impulsivity in children with ADHD (Attention Deficit Hyperactivity Disorder).
Zinc combined with risperidone improved symptoms of schizophrenia in men (e.g., aggression, hallucinations, and delirium). Zinc has antioxidant and antidepressant properties.
It prevents autism
People with autism had lower zinc levels than non-autistic people, according to a study. In this study, zinc and vitamin 6B reduced the severity of autism symptoms (i.e., awareness, hyperactivity, concentration, eye contact, sensitivity to sound, sensitivity to touch, and seizures).
In mouse studies, zinc treatment during pregnancy prevents the development of autistic behaviors (such as social problems, repetitive behavior, and cognitive flexibility), suggesting a link between zinc deficiency and autistic behaviors. Zinc is reversible in autism in brain cells, according to a recent study. According to the study’s author:
We found that even cells with genetic mutations associated with autism can respond.”
Reducing stress and improving mood
Zinc tablets are clinically proven to be effective in treating mood disorders, such as depression and anxiety. They also increase brain-derived neurogenic factor (BDNF), which is low in people with depression.
Zinc consumption improved overall mood by increasing levels of BDNF in overweight people.
Promotes the healing of inflammatory diseases.
Many inflammatory diseases, such as rosacea or red blood vessels, can be treated with zinc. A study conducted on people with rheumatoid arthritis showed that zinc reduced the symptoms of the disease significantly.
Zinc supplements have similar effects on treating other inflammatory skin disorders such as psoriasis and eczema due to its anti-inflammatory and antioxidant properties.
Zinc treatment may be effective in the treatment of dandruff; spasm is a skin disorder that causes the skin to turn brown. Zinc treatment reduces the severity of the disease, minimizes the side effects, and causes skin damage.
A human study found that sunscreen contains more zinc than titanium oxide to protect the skin from premature aging and effectively block UV rays.
Reduce the symptoms of kidney disease.
In patients with chronic kidney disease, zinc consumption improves overall kidney function and reduces many complications. In heart disease, for instance, sexual function is improved by reducing the inflammatory effects of oxidative stress and cholesterol and increasing hemoglobin levels.
Prevent hair loss
Due to its antimicrobial, anti-inflammatory, antioxidant, and anti-androgenic effects on the skin, zinc was found to effectively improve hair growth in bald men in a clinical study.
Women with polycystic ovary syndrome showed that zinc supplementation positively affected several symptoms, including alopecia (hair loss). Additionally, zinc treatment can reduce hair loss in patients undergoing steroid surgery.
Protects the liver from damage
By preventing liver damage mechanisms, zinc supplements effectively treat and reduce liver disease symptoms. With nonalcoholic cirrhosis of the liver, this supplement improves liver function and prevents excessive copper accumulation, which damages the liver.
In addition, they improve patients with hepatitis C, which can lead to liver ulcers if left untreated.
Studies have shown that zinc increases bone density and strength by increasing bone formation and preventing bone loss.
Zinc consumption stimulates bone formation in rat osteoplast cells. In another study, zinc tablets increased bone markers in healthy men. Zinc inhibits bone breakdown markers (such as parathyroid hormone and PGE2) in the bone marrow of cultured mice.
Due to its bone-strengthening effects, zinc protects both animals and humans from many bone-related complications.
Prevention of heart disease
Studies have shown that zinc levels are low in people with hardened arteries, heart disease, chest pain, and those who have had a heart attack. One study found that high rates of heart failure were associated with zinc deficiency.
Other studies have shown that high doses of zinc can prevent and treat angina (chest pain) in atherosclerosis patients. Zinc pills can also protect the heart from stroke damage in mice.
Increased insulin sensitivity
Zinc ions can bind to insulin receptors and activate insulin signaling pathways. It reduces the excess insulin released by pancreatic cells by mimicking insulin, thus protecting pancreatic tissue from damage.
This mineral also improves the solubility of insulin in pancreatic cells and increases insulin dependence on its receptor. Due to zinc’s essential role in the processing, storage, and secretion of insulin, its deficiency can increase insulin resistance.
One study found that diabetics may have low zinc levels. Other studies have found a high percentage of zinc deficiency in type 2 diabetic patients.
Studies in women show that consuming more of this mineral reduces the risk of developing type 2 diabetes. Numerous studies have shown that zinc tablets reduce fasting blood sugar levels and increase insulin sensitivity in animal and human models of diabetes.
The mineral also reduced the severity of diabetic neuropathy (nerve pain), oxidative stress, and triglyceride levels in type 2 diabetics.
Help you lose weight.
Leptin is a hormone that plays an essential role in controlling appetite and weight. Zinc restriction reduces the production of leptin from fat cells in mice and humans. Improving the level of this mineral in men with zinc deficiency increases blood leptin levels.
Zinc protects the body against radiation toxicity in mice and bone marrow-producing cells. Reduces oxidative stress (measured by MDA levels) and stabilizes antioxidant enzymes in rat red blood cells after exposure to radioactive iodine.
Zinc therapy is also able to protect mouse sperm cells from radiation-induced cell death.
Reduce body odor
Bromidrosis (body odor) is usually accompanied by an increase in the bacterial flora – which mainly contains staphylococci and the bacterium chain – in the axilla. Clinical studies have shown that zinc effectively reduces foot and armpit odor due to its antibacterial effect when used topically.
Increase health and fertility in men
Zinc concentration in sperm is positively correlated with sperm count and motility. Zinc’s effect is likely due to its role in stabilizing cell membranes and DNA of sperm cells (by reducing oxidative damage) and increasing spermatogenesis (new sperm cells).
The reproductive function of mice appears to be improved at low to moderate doses. The prostate and testicles contain high levels of zinc, which is involved in testosterone synthesis.
Taking zinc pills increases sperm count, testosterone, dihydrotestosterone (DHT), and fertility in infertile men. Zinc may increase libido and sexual function in men with erectile dysfunction (often also low in testosterone).
Zinc also reduces oxidative damage to the testicles. Zinc can maintain testicular function in mice under oxidative stress (such as testicular weight, sperm concentration, and testosterone levels).
Improve oral health
Zinc deficiency can lead to excessive plaque formation and worsen gum disease inflammation. Plaque growth can be reduced by using mouthwashes containing zinc.
A study of children in slums found that consuming 15 mg of zinc daily for ten weeks reduced dental plaque.
Help prevent cancer
A zinc deficiency is linked with cancer of the mouth, esophagus, and stomach; gastrointestinal tissues are more susceptible to this disease since they are exposed to toxins. Cancers of the head, neck, lungs, prostate, bladder, and ovaries are also linked to zinc deficiency in the blood. In order for tumor killer cells to function, the average surface of the body must be restored.
It can also stop tumor growth by inhibiting glucose uptake, preventing new blood vessels from forming, and causing cell death in animal and human cancer cells.
Has antimicrobial properties
High doses of zinc inhibit the growth of several species of bacteria, especially gram-positive bacteria. It also binds antibacterial activity against aerobic and anaerobic bacteria in the root canal and prevents Staphylococcus aureus growth.
Zinc has also been shown to inhibit the growth of typical wound flora in rats.
Help treat epilepsy and prevent seizures.
Numerous studies show that zinc levels are deficient in epilepsy patients. Zinc treatment reduced seizures in 31% of children with epilepsy.
Additionally, zinc tablets can reduce the delay (periodic between seizures) of fever attacks in mice.
Improve the growth process
Studies have shown that the pill has a significant impact on children’s weight and height, especially with low-weight and short-lived children. In growth studies in children, a dose of 10 mg of zinc per day for 24 weeks resulted in a net increase of about 0.37 cm in children receiving zinc tablets versus children taking a placebo. Zinc also increases muscle mass in children.
Protect the gastrointestinal tract
Various animal and human models have shown that this pill has a protective effect on gastrointestinal tract diseases (such as inflammatory bowel disease, cancer, alcohol poisoning, and colitis). The intestinal healing process stabilizes the nasal mucosa and reduces gastric and small intestinal lesions in mice.
Zinc protects the intestinal mucosa from alcohol-induced damage in mice as well. In addition to eliminating intestinal leakage, it may also reduce the risk of inflammatory bowel disease.
In indigestion patients, Helicobacter pylori-induced gastric cancer inflammation was negatively correlated with zinc levels. By controlling gastritis, zinc increases the risk of gastric cancer.
Help improve sleep quality.
A study in infants found that zinc pills can improve sleep duration for women and children with higher zinc levels in the blood.
Help stimulate appetite and treat nervous appetite.
Loss of appetite is one of the first symptoms of zinc deficiency. In mice, oral zinc supplementation stimulated food intake.
Anorexia nervosa patients show a significant correlation between this disease and low zinc levels in the blood. Zinc supplementation has been associated with weight gain, muscle mass, appetite, taste sensitivity, and food intake in patients with AN.
Increase skin health
Zinc is beneficial for treating a variety of skin conditions (including acne, warts, rosacea, eczema, psoriasis, spasms, and dandruff). The zinc pills (oral zinc) groups experienced a significant improvement in acne compared to the placebo groups.
Zinc pills have been shown in clinical trials to completely eradicate warts in most patients with viral warts. Zinc is also effective in treating herpes simplex (genital warts caused by the herpes simplex virus 1 and 2).
Zinc may reduce the symptoms of rosacea (a chronic inflammatory disease characterized by tiny blood vessels and red bumps on the face).
Fight against extreme fatigue.
Zinc deficiency is associated with many chronic fatigue syndrome symptoms (such as fatigue, depression, and difficulty concentrating). In one study, zinc levels were significantly lower in people with chronic fatigue syndrome (CFS) than in controls. Severity of symptoms was negatively related to zinc levels in the blood.
According to this study, zinc might reduce CFS symptoms due to its antioxidant and anti-inflammatory properties.
There is a joint inflammation of the gut (caused by a leak in the heart) among people with chronic fatigue syndrome. Treatment of intestinal leakage with anti-inflammatory and antioxidant agents, including zinc, significantly improved the symptoms of patients with CFS in one study.
Control and prevention of blood clots
Zinc regulates thrombotic (clot formation) and anti-thrombotic (anti-clotting) factors in platelets and pulmonary blood flow in humans.
Hypersensitivity (high zinc levels in the blood) can cause blood to clot, while hypoxemia (low zinc levels in the blood) can prolong blood clotting time. Both conditions result in abnormal bleeding.
In one study, repairing zinc levels in men with zinc deficiency led to normalized platelet aggregation and blood clotting time.
Improving pregnancy outcome
Zinc levels in the blood are associated with pregnancy complications (e.g., miscarriage, preeclampsia, prolonged pregnancy, preterm delivery, and abnormal fetal growth). Zinc pregnancy supplements (in women with zinc deficiency or underweight women) have been shown to reduce the risk of preterm birth.
In one study, zinc pills were found to cause longer pregnancies and heavier babies in Indian mothers. Zinc tablets (25 mg per day) significantly increased infants’ weight in the second half of pregnancy in pregnant women with low zinc levels in their blood.
Improving women’s health
A zinc deficiency is associated with hormonal disorders that can result in ovarian dysfunction, menstrual irregularities, and infertility. Studies have shown that oral consumption of zinc (mefenamic acid only) can reduce its severity and duration. Menstrual pain occurs during this time.
The reduction in painful cramps in the lower abdomen is probably due to prostaglandins being inhibited by zinc in the uterus. Insulin resistance causes baldness, hair growth, irregular menstruation, and infertility in women with polycystic ovary syndrome.
Zinc tablets have been shown to lower insulin levels and improve symptoms (such as hair growth and baldness) in women with PCOS.
Women with endometriosis (in which intrauterine tissue grows outside the uterus) have low zinc levels in their blood.
Help relieve pain
Zinc has been shown to have analgesic properties in animal studies. Depending on the dose, zinc chloride injections significantly reduce sciatica pain sensitivity.
In another study, zinc-containing salts relieved mice’s pain in response to several painful stimuli (such as chemicals and heat).
It reduces the frequency and severity of muscle cramps in patients with chronic liver disease. By acting as an antagonist to NMDA receptors, zinc is believed to alleviate some of the pain caused by NMDA receptor binding.
Reduce tobacco addiction
Smokers have low zinc levels, and studies in mice have found that zinc reduces the severity of morphine (drug) dependence, whereas zinc uptake increases withdrawal symptoms.
An article in a review of previous research showed that zinc tablets may reduce the risk of addiction among people using chronic pain relief due to their pain-reducing effects and low toxicity.
Increased taste sensitivity
is associated with zinc deficiency. (or carbonic anhydrase VI), a zinc-dependent enzyme, may be less active when zinc concentration in the saliva is low.
According to one study, zinc supplements increased taste (measured by the salt detection threshold) in Indian adolescent girls (often zinc deficient).
Avoid blindness and eye health problems.
Macular degeneration is one of the leading causes of blindness in the elderly due to oxidative stress. Research has shown that zinc tablets can prevent oxidative damage to the retina, slowing the progression of the disease.
Zinc protects the eye against diabetic retinopathy (which can lead to blindness) by preventing the death of retinal capillary cells and new blood vessels (growth of new blood vessels).
Zinc has this effect because it is able to reduce oxidative stress and inflammation, which play a key role in the development of diabetic retinopathy. One of the first signs of vitamin A deficiency is night blindness. According to one study, this vitamin may increase vitamin A’s ability to restore night vision in pregnant women (low zinc levels).
Help treat hearing disorders
In mice, zinc deficiency is associated with hearing loss, which can be treated with zinc tablets. As a result, zinc may have protective properties against toxins in the ear (e.g., cochlea and atrium). Tinnitus patients have low zinc levels in their blood. According to one study, taking zinc tablets (50 mg daily) for two months reduced tinnitus severity in 82% of patients.
The addition of zinc to oral corticosteroids in patients with sudden hearing loss was associated with more significant improvements in symptoms than corticosteroids alone.
A study found that zinc supplements could reduce middle ear infections in low-income children.
Increasing life expectancy in humans
Oxidative stress accelerates the aging process, and its main component is copper/zinc superoxide dismutase (Cu/Zn – SOD), a powerful enzyme that neutralizes free radicals.
In one study, worms and mice with genetically high levels of SOD lived longer. Many age-related diseases (such as Parkinson’s disease, Alzheimer’s disease, and cancer) are associated with mutations in the SOD gene.
Inflammation contributes to the aging process, and zinc tablets have been shown to reduce inflammation, oxidative stress, and infection in the elderly.
Zinc is therefore able to increase life expectancy due to its antioxidant and anti-inflammatory properties, especially in the elderly, who are often zinc deficient.
Help treat cystic fibrosis.
Cystic fibrosis is a genetic disorder that can cause respiratory problems, lung infections, and an inability to gain weight. A study in patients with cystic fibrosis showed that zinc tablets could improve lung function, energy intake, and infection rate.
Increase athletic performance
A study in wrestlers showed that strenuous exercise could significantly lower thyroid hormones and testosterone, leading to fatigue and burnout. However, zinc pills can prevent this problem, and this suggests that zinc intake (in physiological doses) may play a role in a person’s athletic performance.
In another study, thyroid hormone consumption (i.e., 3T and 4T) increased resting metabolism. Zinc tablets also prevent the harmful effects of computer monitor radiation on thyroid hormone levels in computer workers.
Reduce the side effects of chemotherapy
Mucosal ulcers are a side effect of chemotherapy and radiation therapy. Studies in patients undergoing chemotherapy and radiation therapy have shown that zinc supplements can reduce oral mucositis severity.
Dysgeusia (sensation of metal taste in the mouth) and disomy (odor change) can also occur during chemotherapy. One study found that consuming 100 mg of zinc daily for 4-6 months improved dystonia symptoms and disomy in patients with carbonic anhydrase deficiency (Dustin).
This effect is because it stimulates the production of carbonic anhydrase VI, an enzyme in saliva involved in the growth of taste buds.
Reduce the risk of metabolic syndrome
Metabolic syndrome is a group of disorders (such as obesity, insulin resistance, high blood pressure, and high cholesterol) that can increase the risk of heart disease and type 2 diabetes. A study in children with metabolic syndrome showed that these pills reduce insulin resistance, oxidative stress, inflammation, blood sugar, cholesterol, and body mass index.
It helps increase mitochondrial function.
In a study in mice, zinc consumption increased the electron transfer system and oxidative phosphorylation in the liver mitochondria, resulting in increased energy production (ATP).
Treatment and relief of arsenic poisoning
A study on patients with chronic arsenic poisoning showed that zinc combined with spirulina extract effectively reduced melanosis and keratosis symptoms.