Medical

cause and symptoms of bone cancer and its treatment

Bone cancer is rare cancer that starts in the bone and is diagnosed around 550 new cases in the UK each year. This condition is different from “secondary bone cancer,” cancer that spreads to the bone after it has formed in another part of the body and affects the patient. The nature of the activity will be complicated for this person.

bone cancer types:

Some of the significant types of this cancer are:

  • Osteosarcoma – The most common type that mainly affects children and adolescents under 20 years of age
  • Nocturnal sarcoma – most common in people between 10 and 20 years old
  • Chondrosarcoma – commonly seen in adults over 40 years of age.

Young people can be affected because the rapid growth that occurs during puberty can lead to bone tumors. The above types of this cancer affect different types of cells, and the kind of treatment and its prospects depend on the type of this cancer you have.

Signs and symptoms of bone cancer:

bone cancer symptoms

This cancer can affect all bones but is more common in the taller bones of the foot or arm. The main symptoms are:

  • Persistent bone pain that gets worse over time and continues into the night.
  • Swelling and redness (inflammation) of more than one bone makes it difficult to move if the damaged bone is close to the joint.
  • Significant mass over bone volume.
  • A weak bone in which a fracture occurs much more quickly than usual.
  • See your doctor if you or your child has persistent and severe bone pain.
  • While more research may be needed to confirm bone cancer
  • What are the risk factors for this cancer?
  • In most cases, it is not clear why a person gets this cancer.
  • You have been exposed to radiation therapy.

Lee Freeman syndrome has a rare genetic condition in which people have a defective copy of a gene that usually helps cancer cells grow.

The leading causes of different types of bone cancer:

Cancer occurs when cells in a specific area of ​​the body stop and multiply rapidly. This is a mass of tissue known as a tumor. But certain cases can increase the risk of developing the disease, including:

  • Radiotherapy treatment in the past
  • Other bone diseases such as Paget’s disease
  • Rare genetic conditions, such as Li-Fraumeni syndrome
  • History of some other diseases, including retinoblastoma and umbilical hernia

Radiotherapy treatment

Exposure to radiation therapy during radiation therapy may later cause cancerous changes in the bone cells.

Bone condition

Some noncancerous (benign) diseases that affect the bones may increase the risk of developing these cancers. A condition called Paget’s disease can increase the risk of bone cancer in people over the age of 50-60. Milder conditions that cause tumors to grow in the bones, such as Oliver’s disease, can also increase the risk.

Genetic conditions

A rare genetic condition called Li-Fraumeni syndrome increases the risk of this cancer and different types of cancer. People with this syndrome have a defective sample of the gene that usually helps stop tumor growth in the body.

Other conditions

People with a rare childhood eye cancer called retinoblastoma may develop this cancer because their defective genes are the same. Research has also shown that babies with hernia problems are three times more likely to suffer from a type of this cancer called Ewing’s sinusitis, although the risk is still shallow.

Secondary bone cancer:

 This cancer results from the extraction of cancer cells from a primary tumor elsewhere in the body. This type of this cancer results from cancer cells that spread from the primary tumor to the bone elsewhere in the body.

Sometimes only one part of the bone is affected, but in some people, cancer has spread to several factors and is known as secondary bone cancer. This cancer occurs in different parts of the body, and not all secondary cases cause symptoms or problems.

The most common types of cancer:

  • Breast
  • prostate
  • Lung
  • Thyroid
  • Kidney

Symptoms of secondary bone cancer may include:

  • Bone pain – The most common symptom of secondary cancer is a pain in the affected area, which may be mild and persistent, which may be annoying during the day and at night, and there may be swelling and tenderness in the area. If you have this type of pain and it lasts for more than 1-2 weeks, tell your doctor as soon as possible. Although it can appear on several different bones simultaneously, it is usually only one or two painful areas.
  • Bone weakness – Fractures sometimes occur in the case of bone weakness due to cancer, even if you do not have an accident; this is known as a pathological failure.
  • Increased calcium levels – When bones are affected by secondary cancer cells, large amounts of calcium (a substance that helps build bone) may be transferred into the bloodstream. High levels of calcium in the blood are called hypercalcemia. It can cause symptoms such as fatigue, nausea, constipation, thirst, and confusion; however, hypercalcemia is often diagnosed with a blood test before the symptoms are diagnosed.

Stress on the spinal cord – If secondary bone cancer affects the spine, it can pressure the spinal nerves.

Other symptoms:

Sometimes this cancer can cause extreme fatigue, and occasionally secondary bone cancer affects bone marrow function. Bone marrow contains substances that fill bones and produce blood cells. Has different types of blood cells:

Red blood cells carry oxygen to the body.

White blood cells, which help fight infection and disease.

Platelets that cause blood to clot and prevent bleeding.

If the bone marrow cannot produce red blood cells, the person may have anemia, which can cause fatigue and shortness of breath. If your white blood cell count drops, you are more likely to get an infection and an immune deficiency disease. And if the platelet count is low, bruising or persistent bleeding may occur.

How is bone cancer treated:

Treatment for this cancer depends on the type of this cancer and its prevalence.

Surgery to remove the cancerous part of the bone – It is usually possible to repair or replace a removed bone, and sometimes it must be cut.

Chemotherapy

Treatment with solid suppressive drugs

Radiotherapy

Where radiation is used to kill cancer cells

What determines the success of bone cancer treatment?

The cure for the disease depends on age, the type of this cancer, the extent of cancer (stage), and the likelihood of its further spread (degree). In general, about 6 out of 10 people with bone cancer live at least five years after diagnosis, and many may be completely cured.

Discover a cure for bone cancer:

bone cancer treatment

New research by British researchers raises hopes for people with bone marrow cancer Researchers at the Newcastle Hospital Foundation have found that adding elotuzumab to standard treatment for multiple myeloma can reduce the risk of developing the disease by nearly a third.

According to detailed studies, the drug binds to the SLAMF7 molecule in cancer cells and enables the immune system to activate natural killer cells to target and kill myeloma.

“With this drug, a new era in the treatment of bone marrow cancer has begun, and patients can live with less pain and longer,” said a professor of clinical hematology at the Newcastle Hospital Foundation.

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